Spectral Computed Tomography and Low-Dose Image Reconstruction Techniques

Computed tomography is one of the most important imaging techniques that can be used to create high-resolution, high-contrast 3D images of patients in a short space of time. The frequency of CT examinations is constantly increasing, but this also leads to an increased exposure to radiation in civilization. In addition to the problem of increasing radiation exposure, there is also a need for improvement in imaging. The presence of metallic implants can lead to issues with image reconstruction, particularly when they cause hardening and complete photon absorption (beam starvation), which - depending on their severity - can lead to streaks and changes in the area surrounding the implant, and can also make the images non-evaluable.

Modified imaging techniques combined with spectral CT are intended to improve diagnostic image quality and reduce radiation exposure at the same time. The main objectives of this sub-project are to improve the signal-to-noise ratio for improved tissue differentiation, to reduce artifacts in the imaging of metal implants, and to investigate the possibilities of reducing contrast agents. In each case, the possibilities for reducing radiation exposure will also be determined. This has the potential to improve diagnostics and therapy for a larger group of patients while at the same time reducing radiation exposure. The reduction of metal artifacts will also be directly applied in subproject T, where anthropomorphic test specimens with neuromodulation electrodes will be developed.